Weekly Signal: 17

Table of Contents

• Weekly Signal

• Complete our community challenge

• Refer a Neurohacker

• Help us Improve

🧠 Weekly Signal

Neurotechnology News | July 19 – July 25, 2025

Let’s cut through the noise this week.

This week in neurotechnology, we saw credible forward motion across the field. A new ALS trial received international regulatory backing, non-invasive brain stimulation improved memory in older adults, and Neuralink announced plans for global trials and commercial scaling. At the same time, U.S. states are laying the groundwork for brain-data privacy legislation. The pace is measured—but the trajectory is clear.

🧠 SCIENCE & CLINICAL TRIALS

🟢 Masitinib ALS Trial Receives European Approvals

Published: July 24, 2025
Read more ➡️ ALS News Today / AB Science Press Release

AB Science received approval from regulators in Spain, Greece, and Slovenia to begin a confirmatory Phase 3 trial of masitinib combined with riluzole in ALS patients. The study will include 408 participants and aims to validate earlier findings of slowed progression and improved survival.

💡 Big Picture: A new disease-modifying option for ALS may be on the horizon—with regulatory support catching up.

🟢 AI Neuro-Decoder Translates Brain Signals into Speech

Published: July 24, 2025
Read more ➡️ BioRxiv Preprint

Meta AI and UCSF introduced a non-invasive brain-computer interface that uses EEG and deep learning to translate brain signals into full sentences with 82% real-time accuracy. The system could help people with locked-in syndrome or advanced ALS regain communication.

💡 Big Picture: This is a practical step toward scalable, speech-restoring BCIs—without brain surgery.

🟢 Vagus Nerve Stimulation Enhances Memory in Older Adults

Published: July 22, 2025
Read more ➡️ Nature Scientific Reports

A randomized cross-over trial found that transcutaneous auricular vagus nerve stimulation (taVNS) improved verbal and visuospatial working memory in older adults with hearing loss. Participants showed faster response times and greater accuracy after stimulation.

💡 Big Picture: Non-invasive neuromodulation may become a viable way to support cognitive aging without drugs.

🟢 PoNS Device Shows Positive Stroke Rehab Results

Published: July 21, 2025
Read more ➡️ NeurologyLive / Helius Press Release

Helius Medical reported successful results from a registrational trial of its PoNS device, which delivers tongue-based neurostimulation. Stroke survivors in the trial saw statistically significant improvements in balance and gait, prompting a planned submission to the FDA.

💡 Big Picture: A novel, portable neurostimulation therapy may soon support stroke rehab outside the clinic.

💼 INDUSTRY & STARTUPS

🟢 Neuralink Eyes $1B Revenue and 20K Implants by 2031

Published: July 23, 2025
Sources: American Bazaar / Reuters

Neuralink’s internal roadmap outlines plans for 20,000 annual BCI implants and $1 billion in revenue by 2031. It includes device variants like Telepathy (motor control), Blindsight (vision), and Deep (psychiatric therapy) with regulatory approvals projected by 2029.

💡 Big Picture: Neuralink is betting on scaled BCI deployments across medical and elective markets—but timelines remain long.

🏛️ POLICY & ETHICS

🟢 U.S. States Enact Brain-Data Privacy Laws

Published: July 23, 2025
Sources: KFF Health News / Arnold & Porter Advisory

Colorado, California, and Montana have passed laws classifying brain-derived data as sensitive, requiring explicit consent for its collection, use, or sale. Colorado’s version is the strictest, while watchdog groups found that many consumer neurotech products still share neural data with third parties.

💡 Big Picture: These early laws are setting the stage for mental privacy as a new frontier in digital rights.

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