Weekly Signal: 27 | BCI Gains, DBS Updates & Policy

Clinical signals, market moves

Table of Contents

🧠 Weekly Signal

Breakthroughs & Policy Moves

Neurotechnology News | Sep 27–Oct 3, 2025

Let's cut through the noise this week!

This week, we saw a peer-reviewed, minimally invasive 1,024-channel cortical interface demonstrated in humans and a nanoparticle therapy that extends intracortical signal quality. Meanwhile, MRI-native neurosurgical robotics and virtual neurology attracted new capital. In policy, U.S. senators proposed an FTC study on neural data and Belgium expanded nVNS access. Bottom line: safer BCIs, stronger privacy guardrails, and pragmatic market momentum are converging.

🧠 SCIENCE & CLINICAL TRIALS

🟢 Minimally invasive 1,024-channel cortical array shows intraoperative decoding

Published: October 2, 2025

Read more ➡️MassDevice / Nature

Precision Neuroscience reported a thin-film micro-electrocorticography (µECoG) array implanted via a 0.5–0.9 mm “cranial micro-slit” in minipigs and used intraoperatively in five patients. Binary detection of speech onset reached 79.8% accuracy from 4 minutes of training (54 utterances); the same electrodes also delivered sub-millimeter stimulation.

💡 Big Picture: Demonstrates a path to scalable, reversible cortical brain–computer interfaces (BCIs) without craniotomy for mapping and future assistive communication.

🟢 Platelet-inspired nanoparticles improve intracortical microelectrode performance in vivo

Published: September 29, 2025

Read more ➡️ Bioengineer.org / Nature

In rats, weekly systemic dexamethasone-loaded, platelet-inspired nanoparticles improved active-electrode yield by 36% (weeks 1–4) and 82% (weeks 5–8) versus control, and preserved local neuron density (59% vs 21%). Results point to reduced neuroinflammation and blood–brain barrier leakage as mechanisms.

💡 Big Picture: Targeted systemic nanotherapy could extend the useful life of intracortical BCIs and lower failure-driven revision rates.

💼 INDUSTRY & STARTUPS

🟢 AiM Medical Robotics closes $8.1M Series A for MRI-compatible neurosurgery

Published: September 30, 2025

Read more ➡️ MassDevice / AiM Medical Robotics

Funding will support the first human study of AiM’s intraoperative MRI-guided robot aimed at precise device placement and addressing brain shift in functional neurosurgery. The system targets indications like Parkinson’s disease neurostimulation and aims to eliminate patient transfers between OR and imaging suite.

💡 Big Picture: MRI-native robotics could standardize stereotactic workflows and reduce time-to-therapy in hospital neurosurgical programs.

🟢 Neura Health raises $11.4M Series A; first investment from AHA’s Go Red Fund

Published: September 29, 2025

Read more ➡️Neura Health / GlobeNewswire

The virtual neurology clinic will scale nationally, expand memory care, and deepen payer and health-system partnerships; total funding reaches $22M. Neura reports 43,000 patients served and coverage with 40+ plans, positioning for broader specialty access.

💡 Big Picture: Virtual-first neurology is maturing into enterprise partnerships, broadening intake for specialty care and real-world data generation.

🏛️ POLICY & ETHICS

🟢 U.S. senators introduce the MIND Act to direct FTC neural data study

Published: September 29, 2025

S.2925 would require the Federal Trade Commission to study governance of neural data—covering implanted BCIs, wearables, and inferred signals—and report within a year, then annually. The bill tasks FTC and OSTP with guidance for federal agency use.

💡 Big Picture: Lays groundwork for a federal baseline on neural data practices before mass-market neurotech scales.

🟢 Belgium adds reimbursement for gammaCore (nVNS) in cluster headache

Published: September 29, 2025

Read more ➡️ GuruFocus / electroCore

Belgium’s RIZIV/INAMI added long-term reimbursement for gammaCore Sapphire non-invasive vagus nerve stimulation effective Oct 1, 2025, expanding access for cluster headache patients. Decision cites clinical and economic evidence and may influence nearby markets.

💡 Big Picture: Payer recognition of neuromodulation strengthens the case for non-pharmacologic headache care across the EU.

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